Postfix Transport question

It seems more and more ISP's and companies are beginning to block IP's on the MAPS DUL - which I bet blocks more legit mail then it does spam, but I suppose each ISP has it's right to choose what mail to accept and reject. Anyway, I grow tired of manually adding these to the transport file, and I don't want to resort to relaying ALL my mail through my ISP's mail server.

So, my question, Is it possible to configure postfix to behave in such a fashion that if it gets a 550 error, it will try again, this time relaying through a predetermined host?

Thanks,

-Jim

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